ABI3BP Antibody, HRP conjugated

Datasheet

Code	CSB-PA772035LB01HU
Size	US$166
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) ABI3BP Polyclonal antibody

Uniprot No.

Q7Z7G0

Target Names

ABI3BP

Alternative Names

ABI gene family member 3 (NESH) binding protein antibody; ABI gene family member 3 binding protein antibody; ABI gene family member 3-binding protein antibody; ABI3BP antibody; FLJ41743 antibody; FLJ41754 antibody; Nesh binding protein antibody; Nesh BP antibody; Nesh-binding protein antibody; NeshBP antibody; Target of Nesh SH3 antibody; Target of Nesh-SH3 antibody; Tarsh antibody; TARSH_HUMAN antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Target of Nesh-SH3 protein (601-900AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

HRP

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Gene References into Functions

ABI3BP is a susceptibility gene for Kashin-Beck disease in the Chinese Han population. PMID: 24442417
Thus, TARSH presumably represents a trigger gene for evoking cellular senescence, which has also been suggested to be involved in the prevention of tumorigenesis. PMID: 15752759
expression of TARSH mRNA is remarkably downregulated in all lung cancer cell lines examined; also TARSH expression was significantly low in all of the tumor specimens when compared to the expression in corresponding non-neoplastic lung tissue specimens PMID: 16205947
The loss of ABI3BP expression could play a functional role in thyroid tumorigenesis. PMID: 18559958
These results suggest that TARSH plays an important role in proliferation of replicative senescence and may serve as a trigger of tumor development. PMID: 19338757

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Involvement in disease

Defects in ABI3BP has been found in a patient with isolated coloboma, a defect of the eye characterized by the absence of ocular structures due to abnormal morphogenesis of the optic cup and stalk, and the fusion of the fetal fissure (optic fissure). Isolated colobomas may be associated with an abnormally small eye (microphthalmia) or small cornea.

Subcellular Location

Secreted.

Tissue Specificity

Expressed in brain, heart, lung, liver, pancreas kidney and placenta.

Database Links

HGNC: 17265

OMIM: 606279

KEGG: hsa:25890

STRING: 9606.ENSP00000284322

UniGene: Hs.477015

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Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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